This report was commissioned jointly by the National Road Transport Commission of Australia, the Australian Transport Safety Bureau and the New Zealand Land Transport Safety Authority. The fatigue expert group comprised leading Australian and New Zealand experts in sleep, shiftwork and road safety who collaborated with the participating agencies and industry representatives to construct a set of evidence-based design principles for future fatigue regulatory options. The group considered that the management of driver fatigue is not a matter for operators and drivers alone, and emphasised the requirements and practices of others in the transport supply chain.