In Slovenia the legal regulation enable the police to execute a medical examination with analysis of urine and blood samples and the toxicological analyses of biological material in cases of concrete suspicion of driving under the influence. The data collected (drugs pattern, age, gender, hour and day of offence) is a contribution to the general knowledge of the epidemiology of drugs in Slovenia. A progress is made in recognition of persons driving under the influence of drugs. An advantage in our work is the small population of our country and the knowledge of local factors. Since the driving licence is becoming more and more a status of a general education the driving under the influence of drugs is very often one of the deeds in which the young drug abusers also appear for the first time as lawbreakers. Both in cases involving alcohol and even more in cases involving drugs we have noticed an increase of number of traffic participants, who will decide to drive while intoxicated regardless of the amount of penalty. Our efforts for better safety and more humane relationships in road traffic are therefore not directed only in recognition, detecting and sanctioning of driving under the influence of drugs but also in searching the connections and the solutions for possible directing of young delinquents drug users and drug addicted in programmes of medical and psychological help, treatment and rehabilitation.