We describe the organisation of an information and prevention campaign that was launched in Belgium in 1999 to inform health professionals and the general public about the possible influence of medicines on driving abilities. A brochure was distributed to the public in pharmacies and doctor s offices; all physicians and pharmacists received a compact professional brochure. A scientific report containing literature data of 179 medicines, with categorisation in 7 classes according to the impairing effect, was available for a small fee. The campaign was introduced by a press conference. Both brochures proved to be a success with much interest from public and (non-) professionals.