It is increasingly being recognized at all levels of decision making that freight transportation and economic development are inextricably linked. As a result, many urban entities and states are embarking upon comprehensive freight transportation planning efforts aimed at ensuring safe, efficient, and smooth movement of freight along multimodal and intermodal networks. Over the past few decades there has been considerable published research on (1) freight transportation factors, (2) freight travel demand modeling methods, (3) freight transportation planning issues, and (4) freight data needs, deficiencies, and collection methods. A synthesis of the body of knowledge in these four areas is provided with a view to developing a comprehensive statewide freight transportation planning framework. The proposed framework consists of two interrelated components that facilitate demand estimation and decision making in the freight transportation sector.