Aiming at process, mode and characters of urban road traffic safety management, four database modes of DSS integrated decision support system theory and technology, and they were adopted to collect, analyze, manage, decide and feed back road traffic safety information. The function and structure of this system were studied according to the general building process of management on DSS. Based on this, the main parts and constructional methods were decided. The system was designed from seven parts: integrated road traffic safety information management subsystem, accident causation analysis subsystem, traffic accident prediction subsystem, traffic incident management and alarming in advance subsystem, safety evaluation subsystem, safety countermeasures subsystem, economic analysis and decision subsystem. The data management and realization, modal realization, and man-machine interface, etc. were designed, and an case was studied to integrate program development flow.