Current and near-term technologies that support real-time emergency response to car crashes are described. A vision for emergency response and rescue as it might appear in 20 years under a fully integrated active transportation system (IATS) is provided. First, a baseline on which to build such a vision is established. Response to a single-casualty or multicasualty motor vehicle crash was selected as a specific use case. A systems approach was used to divide the emergency response process into individual functional steps. Key issues and desired capabilities are identified for each step. Technologies that fall into three categories - state of the practice, state of the art, and future art - are identified. The intent is to determine where research efforts might best be focused to make a generational leap in emergency response capabilities. A vision is described for the future of emergency response and rescue, which could be realized by 2030 as part of the planned IATS. Work is continuing to assess functional needs and potential future technologies (including cyberphysical systems), after which specific areas will be targeted for focused research and development.